Best Enzymatic Cleaners: The Top 13 For 2023

Best Enzymatic Cleaners

Despite the promise of a clean house, many cleaning products on the market are full of toxic chemicals. Think about using enzymatic cleaners as an alternative to regular household cleaners if you’re looking for a non-toxic alternative. Enzymatic cleaners use biologically active chemicals to break down stains, messes, and odors in your house.

But if you aren’t sure what to look for, it can be tough to choose the right enzymatic cleaner. There are many eco-friendly cleaning products on the market, so how do you decide which is best for your home?

Our mission is to make shopping as easy as possible for our readers. Because we buy our own products rather than accepting free products from manufacturers, our recommendations are honest and unbiased. The shopping guides we compile are the result of testing products in our labs and on the field, consulting our team of experts, and analyzing customer feedback, so you will have information that is relevant to your shopping decisions.

Take a look at our top picks if you’re in the market for an enzymatic cleaner in 2023. Keep reading for more information about what to look for when purchasing an enzyme cleaner.

1. Simple Solution Extreme Pet Stain And Odor Remover

Simple Solution Extreme Pet Stain And Odor Remover


  • Brand: Simple Solution
  • Model: ‎10137N-12PONL
  • Style: Original
  • Weight: 2.27 Pounds
  • Dimensions: 4.5 x 2.75 x 11.12 inches
  • View at Simplesolution

Would you like to know a simple way to remove pet stains and odors? Even if your pet is pet trained, it takes a lot of effort and time to scrub the carpet or home furnishings. You may also find that regular products are insufficient if a stain is extremely stubborn.

Pet stain and odor removal are very easy with Simple Solution Extreme Pet Stain and Odor Remover, as its name indicates. Thanks to the convenient spray bottle included with this product, this is guaranteed. The cleaner’s spray can be directed exactly where it is needed because of this.

You can also customize how much product you want to apply with the 3-in-1 sprayer. A nozzle can be set to produce mist, foam, or stream by simply turning the knob. Whatever pest problem you are looking to solve, this product will fulfill your needs.

Added to that, it will be quick to get the job done with this cleaner. The new Pro-Bacteria formula found in Simple Solution Extreme Pet Stain and Odor Remover works quickly and effectively. There’s evidence to suggest that it’s three times stronger than many competitors.

If you or a loved one suffer from sensitive skin, you may want to steer clear of this product. Several ingredients in this formula have been shown to irritate the skin. After washing the product, you can resolve the problem by rinsing thoroughly, as this could cause residue.

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2. Angry Orange Enzyme Cleaner for Home Use

Angry Orange Stain Enzyme Cleaner


  • Brand: Angry Orange
  • Scent: Citrus
  • Form: Drop
  • Weight: 2 Pounds
  • Dimensions: 10 x 6.34 x 3.31 inches
  • View at Angryorange

A premium enzyme cleaner that can be used to eliminate livestock odors, Angry Orange Stain Enzyme Cleaner is the perfect solution for odor removal. The oil found in orange peels is a non-toxic ingredient in Angry Orange, unlike other enzyme cleaners.

A second benefit is that the cleaner does not have a citrus smell, which is much better than other cleaners. Cleaning with the Crazy Orange cleaner not only cleans carpets and hard floors, but also eliminates odors from bushes and grass.

In addition, this enzyme cleaner completely eliminates all traces of cat odor, including the ammonia smell that remains after cleaning. As a result, this enzyme cleaner can be one of the most suitable choices for those seeking a natural and safe odor remover.

3. Nature’s Miracle Urine Destroyer for Dogs

Nature's Miracle Urine Destroyer for Dogs


  • Brand: Nature’s Miracle
  • Model: ‎P-5727
  • Style: Original Formula
  • Weight: 2.25 Pounds
  • Dimensions: 3.38 x 3.37 x 9.25 inches
  • View at Naturesmiracle

Founded over 30 years ago, Nature’s Miracle was originally created to manufacture safe and effective cleaning products for preschools. Pet parents throughout the world quickly recognized this brand with its distinctive bright red bottle and bright red cap, due to its safe and effective enzymatic formula.

Among the first enzymatic formulas to be introduced to the general public, it was one of the only ones available. This makes it an especially popular brand among schools and households with younger children since its formula is pet- and family-safe. Nature’s Miracle has grown to offer pet and human stain and odor removal sprays and products since the company was founded.

A variety of settings use it, from homes to health centers to veterinary clinics. In addition to litter, waste management aids, and potty training aids, you can purchase for your kittens and puppies to prevent them from having accidents. It is possible to purchase Nature’s Miracle products online, at pet specialty stores, and at several large retailers around the world.

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4. AmazonCommercial Multi-Purpose Enzyme Cleaner

AmazonCommercial Multi-Purpose Enzyme Cleaner


  • Brand: AmazonCommercial
  • Model: ‎PBH-342711
  • Scent: Mint
  • Size: 1-Gallon
  • Weight: 8.6 Pounds
  • Dimensions: 6.1 x 6.1 x 11.68 inches

You will find Amazon’s Multi-Purpose Enzyme Cleaner to be the best choice to remove dirt and grime from carpets and rugs. Cleaning with this multifunctional cleaner will brighten your house and make it clean.

A multipurpose enzyme cleaning solution that cleans diverse surfaces because it removes pet odors, stains, and complex organic proteins in seconds. This means that you can clean your surfaces quickly.

Also, this cleaner will provide you with better results when it comes to hair, grease, and oils on your carpet, so cleaning thick carpets and mattresses will be much quicker with this cleaner. Once it’s finished cleaning, it emits a mint smell.

5. Sunny & Honey Enzyme Cleaner

Sunny & Honey Pet Stain & Odor Miracle


  • Brand: Sunny & Honey
  • Model: ‎Enzyme Cleaner
  • Size: 32 FL OZ
  • Scent: Spring Mint Scent
  • Weight: 2.29 pounds
  • Dimensions: 10.7 x 4.9 x 2.9 inches

When it comes to cleaner products, you need to choose them carefully if you have sensitive skin. Even cleaning products use harsh chemicals to accomplish their tasks, they can irritate your skin. The cleaner chemicals can also spread through fabrics and make carpets fade rapidly.

It won’t be a problem when you use the cleaner from Sunny & Honey. A natural cleaner that eliminates pet stains and odors quickly and permanently. Its drying characteristics are mild on any fabric or skin type, and it can be used on a range of surfaces.

You will no longer have to ask your guests this question every time they enter your home. This pet stain and odor remover cleaner works quickly to effectively eliminate unpleasant pet odors. You will enjoy the fresh, minty scent that it leaves behind.

Like any cleaner that comes with a scent, taste plays a role in choosing one over the other. This product gives off a fresh, minty smell, which is loved by many of its cleaners users. While it is a rather strong scent, you may want to avoid it if you do not enjoy mint.

There are other offerings of Sunny & Honey Pet Stain & Odor Miracle. With the fall spice scent, you can expect a lighter and more floral aroma. If you’re allergic to perfumed best cleaners products, there are fragrance-free alternatives available.

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6. Nature’s Miracle Dog Stain And Odor Remover

Nature’s Miracle Dog Stain And Odor Remover


  • Brand: Nature’s Miracle
  • Model: ‎P-98314
  • Size: 32 Fl Oz
  • Style: Updated Formula
  • Weight: 2.23 Pounds
  • Dimensions: 9.61 x 4.06 x 2.44 inches

The problem isn’t just removing urine from carpets or upholstery; it goes much deeper. You want to avoid having to repeat this process frequently. You actually need a clever way of keeping your pet away from your domestic because they tend to pee inside.

Stain and odor removal are two services offered by Nature’s Miracle Dog Stain and Odor Remover in one convenient product. Using the special formula, you can eliminate pet urine ammonia by targeting the bacteria. This product has been infused with the lemon scent so that pests will not be tempted to urinate in that location.

With this product, no scrubbing or blotting is necessary. You need only place a small amount of the product on the desired area or skin and wait for it to act. The odors are also lifted away when Nature’s Miracle Dog Stain and Odor Remover dries over them.

For this product to fully rid and remove stains and odors, it takes five minutes or less. By permanently eliminating odors, rather than merely masking them, odors are eliminated. Besides rubbing away the nasty residue, there will be nothing else you need to do.

Although it is effective and strong, this cleaner contains some rather unpleasant ingredients. It is important to take extra care when using this product to make sure you do not get it on your skin. A face mask could also be good to wear after applying and leaving the room for several hours.

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7. Trinova Natural Advanced Enzyme Cleaner

Trinova Natural Pet Stain And Odor Remover Eliminator


  • Brand: TriNova
  • Form: Spray
  • Volume: 32 Fluid Ounces
  • Weight: 2.17 Pounds
  • Dimensions: 13.11 x 5.08 x 4.61 inches
  • View at Walmart

Cleaner products must contain harsh and potentially toxic ingredients to work effectively, do you think? If that’s the case, rethink it. Pet stains and odors are eliminated with the TriNova Natural Pet Stain and Odor Remover Eliminator, which is tough on stains while being gentle in the home environment.

We have made this product using only organic and natural ingredients. It is therefore entirely safe to use. Although it may accidentally spray directly on your skin or your pet, you will not experience any adverse effects from it.

This product can easily deal with a stain even after it has been sitting for a few days. You only need a little bit of the product to make the difference. Just spray it on the affected area and it does its work. Due to the spray bottle, the application is effortless as well.

We will replace the unpleasant odor of urine with an herbal scent. As opposed to many products containing harsh chemicals, this odor is fresh and light in nature. Pets have been discouraged from peeing in the same area by using herbs that have been used.

8. Bubbas Super Strength Enzyme Cleaner

Bubbas Super Strength Commercial Enzyme Cleaner


  • Model: ‎32 oz Terminator
  • Scent: Lemon
  • Form: Liquid
  • Weight: 2.2 Pounds
  • Dimensions: 5 x 2 x 10 inches

You could have a serious problem if your pet urinates in your laundry basket. Even when you wash your clothes, this strong and unpleasant smell will remain. If this occurs frequently, you could end up with permanently damaged clothes or an expensive dry cleaning bill.

BUBBAS Super Strength Commercial Enzyme Cleaner can be used in laundry without causing any harm. This method won’t fade colors or leave residues behind. You should be able to spray this product on even delicate fabrics without damaging them.

With the spray bottle that this product comes in, this is an incredibly easy process. Special dormant bacteria are contained in BUBBAS Super Strength Commercial Enzyme Cleaner to combat strong pet urine odors. When the bacteria come into contact with the stain, they are only active, making them extremely efficient.

Whether the odor has been present for a long time or not, you’ll be able to get rid of it quickly. A pleasant floral fragrance will have replaced the disagreeable smell. This enzymatic cleaner must be sprayed directly onto stains to eliminate them. After that, the stain must be left for around 10 minutes before being removed. When faced with an old stain or one that has become particularly tough, however, you may have to wait a little bit longer.

9. Mister Max Unscented Anti Icky Poo Odor Remover

Mister Max Unscented Anti Icky Poo Odor Remover


  • Brand: Mister Max
  • Model: ‎AIP-UN-G
  • Volume: 1 Gallon
  • Weight: 8 pounds
  • Dimensions: 4 x 4 x 12 inches
  • View at Homedepot

Even though products are known for being effective, they can smell quite strong. Sometimes the cleaner’s scent is actually quite unpleasant. Chemicals that certain products use to perform their function can also negatively affect the home environment.

The unscented Mister Max Anti Icky Poo Odor Remover works well without leaving behind chemical odors. The formula neutralizes odors while at the same time you’re domestic. This formula can also be used on delicate fabrics without causing any damage.

This cleaner has a very specific purpose, as its name makes clear. I should clarify that Mister Max Unscented Anti Icky Poo Odor Remover is designed to handle pet waste. Strong odors, stains, and urine from cats are among these.

Spraying this formula directly on a broad range of different surfaces is possible. Shortly, cat urine and other substances will be no more. The likelihood of your pet continues to urinate in the cleaners area is also likely to be reduced.

Note that heavily stained areas may need multiple cleaners. When the stain has been on your carpet for a while, you should let the soaking spray work its magic. As it works, you will however get a light and fresh perfume smell at the end.

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10. Naturally It’s Clean Floor Enzyme Floor Cleaner

Naturally It's Clean Floor Enzyme Floor Cleaner


  • Brand: Naturally it’s clean
  • Model: FBA_BCA66612
  • Form: Liquid
  • Scent: Orange
  • Weight: 4.48 Ounces
  • Dimensions: 3.75 x 8.5 x 2.5 inches

When your hardwood floors get pet or kitty pee all over them and the smell persists, you might consider ripping them out and replacing them altogether. I’m telling you, it can be really bad- just ask anyone who moved into a house that had once been a cat hoarders. Enzymatic cleaners for hardwood floors can dispel the odors for good and remove any stains for good if your pet has had a potty accident on the floor.

We have specially designed Naturally It’s Clean Natural Floor Cleaner to clean all types of flooring, including hardwood floors, laminate floors, tiles, linoleum, and more. You can wipe all your troubles away with a handful of mop strokes after mixing 1oz of this concentrate with a gallon of water.

11. Eco Strong Outdoor Enzyme Cleaner

Eco Strong Outdoor Enzyme Cleaner


  • Brand: Eco Strong
  • Model: FBA_BCA66612
  • Form: Liquid
  • Scent: Orange
  • Weight: 4.48 Ounces
  • Dimensions: 3.75 x 8.5 x 2.5 inches

Outside, where there’s plenty of fresh air and sun, it might seem that pee or poop don’t leave residual scents or stains, but unfortunately, that’s not true. It doesn’t matter if your pooch uses one area of the backyard to do his business or neighborhood cats are marking their territory, the scent you’ll get every time you’re outside is bound to be unpleasant.

A chemical-free formula makes the Eco Strong Outdoor Odor Eliminator ideal for these situations: bio-enzymes will eliminate organic waste odors at the source without damaging surfaces. In addition, this enzyme cleaner for outdoors comes with a spray nozzle with three different spray types that can fit onto any garden hose for an easy cleaning process, regardless of how much surface you have.

12. Simple Green Enzyme Cleaner

Simple Green Enzyme Cleaner


  • Brand: Simple Green
  • Model: 2010000415312
  • Scent: Markings
  • Weight: 8.73 Pounds
  • Dimensions: 7.38 x 4.5 x 11.13 inches
  • View at Simplegreen

Alternatively, the Simple Green Cat Stain & Odor Remover is a great choice if you’re looking for something more affordable. This product comes in three sizes: one gallon, one-quarter gallon, or one 32-ounce bottle. Nearly all surfaces will be permanently odor and stain-free after using this formula.

In addition to urine and feces, Simple Green cleaner also removes vomit, blood, drool, and other organic stains. There are no toxins in it because it’s made with natural enzymes. You will create a safe and clean environment for your children and pets by using it.

Stains and odors can be removed with this cleaner no matter how old or new they are. Unlike our first choice, it doesn’t last quite as long as our second option. Therefore, you can use it for spot cleaning fabric and laundry. I found this to be the best enzyme cleaner for cat urine in terms of price.

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13. Amaziing Solutions Pet Enzyme Cleaner

Amaziing Solutions Pet Odor Eliminator And Stain Remover


  • Brand: Amaziing Solutions
  • Scent: Pleasant Scent
  • Material: Bio-Enzyme
  • Weight: 3 Pounds
  • Dimensions: 6 x 6 x 12 inches
  • View at Amaziingsolutions

Brands that use extra letters to emphasize their greatness are ones with plenty to shout about. Amazing Solutions claims that their Pet Odor Eliminator and Stain Remover is one of the most effective cleaners available.

They don’t fear putting their money where their mouth is with this cleaning product. To promote this product, they have provided a lifetime satisfaction guarantee. If you’re not happy with it for any reason, you can request a refund.

A great feature of this cleaner is its suitability for use on domestic hardwood floors. It not only removes pet stains and odor but also leaves floors sparkling clean. It means that you can stop using your standard floor cleaner.

If you use this cleaner on fabrics, take care not to damage them. The amazing solutions for pet odor remover and stain remover are a combination of powerful and versatile ingredients. A careless approach could lead to faded spots in delicate fabrics and even carpets.

Whenever you run out of Amazing Solutions Pet Odor Eliminator and Stain Remover you won’t have a problem. This cleaner comes in a huge bottle that contains one gallon of solution. A spray bottle might be more convenient since this big bottle can be rather bulky.

Buyers Guide: Best Enzymatic Cleaners

Perhaps you thought that choosing the best enzymatic cleaner was an easy decision. You are after all seeking a product that will eliminate pet urine odors and stains. It is important, however, to consider several factors before buying the perfect product. Now, let’s go over them…

Activating Ingredients

It can differ widely which active ingredients a product uses to accomplish its tasks. The toxic properties of some products are common to all types, and they can have adverse effects on health. If you want to prevent this, it is best to select products that are made from natural and organic ingredients.

Suitability of Surfaces

A few products are designed to be used only on carpets and home furnishing, whereas others work well on a wide range of surfaces. As a rule, it is a good idea to find the best enzyme cleaner that can do several jobs well. The chlorine in the product should not cause the fabrics to fade, so make sure this isn’t the case.

Method of Application

We can only assume that you would like the cleaner product to be as easy to use as possible. Enzymatic cleaners packaged in spray bottles are particularly convenient, especially if they can be adjusted. It also means you won’t have to approach the stain directly to remove it.

The average pour bottle is significantly larger than a spray bottle, and they are generally more affordable. Nevertheless, you will need to approach the stain much closer to apply cleaner. When using a cleaning product that comes in a spray bottle, it may be best to pour some into a pour bottle.

Drying Time

For the majority of cleaner products, it takes twelve to twenty-four hours for them to completely dry. During this time, the domestic area should be avoided completely. Those cleaner products that come with shorter drying times could appeal to you better.

The Scent

You may or may not find the scent appealing, as it really depends on your preferences. Make sure you take the time to think about what flavor you would like your enzymatic cleaner to have. If you are sensitive to synthetic scents, choosing a fragrance-free model could be the best option for you.


The price of enzyme cleaners varies depending on the size of the bottle and how concentrated the formula is, but you can expect to spend between $10 and $50. The average price of an enzymatic cleaner spray bottle is between $10 and $20. You can usually purchase an enzymatic cleaner for $25 to $50 per gallon pour bottle.

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Frequently Asked Questions

What is the best enzyme cleaner?

Which given, all things considered, is the best enzymatic cleaner solution? A cleaner’s product needs to be tough enough to accomplish the task. It is important not to run the risk of harming your health or your pets. As a result of its clean and green formula TriNova Odor Remover Eliminator.
The perfect balance is created by this. An enzyme cleaner is known to be especially effective when it comes to removing urine stains. Using this product will eliminate unpleasant odors without damaging the domestic environment.

How does vinegar work as an enzyme cleaner?

An alkaline solution, white vinegar can help to deodorize areas where pet urine accumulates. Using traditional cleaning methods will not solve the problem of urine stains as they contain organic enzymes that are hard to remove. Cleaning with vinegar is a great way to break down all the enzymes in order to remove all the smells from the area.

How safe are enzymatic cleaners for children and pets?

Because enzyme cleaners contain no toxic chemicals, they are significantly safer than traditional cleaning products. Using enzyme cleaners around children or pets is completely safe. You should however be sure that enzymatic cleaners are stored in a safe place where children and pets cannot reach them.

Would an enzyme cleaner work in a carpet cleaner or steamer?

The use of enzyme-based cleaners in carpet cleaners and steamers is not advised. The extremely high temperatures used in these appliances can interfere with enzyme activity because they heat water and convert it to steam at extremely high temperatures.

Enzymatic cleaners remove what types of stains?

Enzymatic cleaners are effective against a range of organic stains. Besides breaking down blood and urine to remove stains and odors, they can also remove stains and odors from food, including food oils, grease, and wine.

About Emma Gold

Hi, I'm Emma Gold and I am the Blog Editor at My blog is all about kitchen accessories and utensils that you need to make your cooking life easier! If you're looking for a new knife or spatula, or want to upgrade your pots and pans; then come visit me at my blog to see what's hot in the kitchen world today!

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